Grey's Anatomy
Shonda Rhimes developed Grey's Anatomy, an American medical drama. It began on ABC on March 27, 2005, and has been renewed every year since, reaching 22 seasons and 466 episodes. It follows surgical interns, residents and attending physicians through their working and private lives. Its name puns on the surname of lead character Meredith Grey and on Gray's Anatomy, the classic human anatomy textbook by Henry Gray.
The story unfolds at the fictional Seattle Grace Hospital, later renamed Seattle Grace Mercy West and then Grey Sloan Memorial. At the start, attention falls on five interns: Meredith Grey, Alex Karev, Cristina Yang, Izzie Stevens and George O'Malley, overseen by Dr. Miranda Bailey, Dr. Derek Shepherd and surgical chief Dr. Richard Webber. Ellen Pompeo plays Meredith, and the original line-up also featured Sandra Oh, Katherine Heigl, Justin Chambers, Chandra Wilson, James Pickens Jr. and Patrick Dempsey. The cast changed heavily, and by season 19 only Pompeo, Wilson and Pickens remained from the original group.
It films mainly in Los Angeles, partly in Vancouver. It is the longest-running scripted primetime series on ABC, has won Golden Globe and Emmy awards, and has spun off Private Practice (2007–2013) and Station 19 (2018–2024). A 23rd season was announced in March 2026.
| Production company | ShondaLand |
|---|---|
| Network | American Broadcasting Company |
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Also in the cast: Sandra Oh, Katherine Heigl, Justin Chambers, Chandra Wilson, James Pickens Jr.


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